MANUFACTURING

From development to technology and production, FARMIGEA S.p.A. MANUFACTURING can guarantee the highest quality standards to its clients.

The pharmaceutical plant in Ospedaletto (Pisa) is formed by 6 production lines for all kind of ophthalmic presentation:

  • Preservative-free & re-closable single-dose container
  • Preservative-free & multi-dose container
  • Multi-dose container with preservatives
  • Ophthalmic gel and ointment

 

  1. P.F. single-dose container
  2. P.F. multi-dose container
  3. Multi-dose container with preservatives
  4. Gel/ointment

In the 70s FARMIGEA was the first company in Europe to patent and produce the pre-moulded preservative-free reclosable 0,5 ml single-dose vial.

Single-dose containers are marketed in different presentations, according to the quantity of strips in the package itself.

Each strip is formed by 5 single-dose units:

    1 x sachet – 1 strip (5 single-dose units)
    2 x sachets – 2 strips (10 single-dose units)
    3 x sachets – 3 strips (15 single-dose units)
    4 x sachets – 4 strips (20 single-dose units)
    5 x sachets – 5 strips (25 single-dose units)
    6 x sachets – 6 strips (30 single-dose units)

 

1.1 FARMIGEA’s preservative-free single-dose technology

Click on the image below to zoom

daisy small  D3 8184 Strip Mono

 

1.2 Production line

Click here to watch

lineamonodosemonodosesenzaconservanti

With over 20 million packages produced every year (10 mln single-dose and 8 mln multi-dose packages and 2 mln gel/ointment tubes), all our lines are equipped with modern clean rooms fully compliant with European GMPs as well as with the most advanced machineries, in order to guarantee our the maximum performance to our clients.

 

1.3 Comparison between FARMIGEA’s technology and “Blow- Fill- Seal” technology

FARMIGEA’s single-dose definitely stands out from BFS technology, which is ordinarily used to manufacture preservative-free eye drops.

Click on the images below to zoom

sistemiconfronto sistemiconfronto2 sistemiconfronto3 sistemiconfronto4 sistemiconfronto5 sistemi6s sistemiconfronto7

 

If you are interested in having more information about Farmigea and learn about the potential partnership opportunities, contact us at This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Preservative-free multi-dose container is the latest eye drop format in our compendium.

Since the demand for preservative-free eye drops had sharply raised, FARMIGEA started working with Rexam’s NOVELIA, the best preservative-free multi-dose technology in the market.

novelia

 

2.1 Production lines

Click here to watch

multidosesenzacons

 

2.2 NOVELIA system

Click on the images below to zoom

novelia1s novelia2s

If you are interested in having more information about Farmigea and learn about the potential partnership opportunities, contact us at This email address is being protected from spambots. You need JavaScript enabled to view it.

Multi-dose with preservatives eye drop is still the most typical format, widely used for many products, both drugs and medical devices.

conconserv

 

3.1 Production line

(Click here to watch)

  video con cons

 

3.2 FARMIGEA’s multi-dose with preservatives bottles

FARMIGEA can produce 3 bottle formats of multi-dose with preservatives, from 5 to 10 ml:

 

1. Bisio 10ml bottle, with child-proof or tamper-evident caps/closures;

bisio

 

2. Gerresheimer from 5 to 10 ml, with child-proof or tamper-evident caps/closures;

gegghe

 

3. Bormioli 10 ml bottle, with child-proof caps/closures.

bormioli

 

 

If you are interested in having more information about Farmigea and learn about the potential partnership opportunities, contact us at This email address is being protected from spambots. You need JavaScript enabled to view it.

 

The sterile ointment/gel/ production line comprises the following components:

• The pharmaceutical plant in Ospedaletto (Pisa) is formed by 6 production lines for all kind of ophthalmic presentation:
• A turboemulsifier with 300 litre max. capacity;
• A dynamic weighing equipment, packing machine, cartoning machine.

 

4.1 Production line

(Click here to watch)

video gel

 

If you are interested in having more information about Farmigea and learn about the potential partnership opportunities, contact us at This email address is being protected from spambots.This email address is being protected from spambots. You need JavaScript enabled to view it.